Scientist/ Sr. Scientist - Process Sciences

Job Locations US-CA-Thousand Oaks
ID
2020-1316
Category
Process Sciences
Type
Regular Full-Time

Job Description

This position will work in Process Sciences team to develop and characterize allogeneic cell therapy manufacturing processes and products. The PD Scientist/ Sr. Scientist will be responsible for designing and performing laboratory studies to support process development and process characterization of Atara’s T cell products. He/she will be responsible for developing automated cell manufacturing processes, including optimization of bioreactor process parameters and assessment of cell culture reagents. Under minimal supervision, you will be expected to design and perform experiments, organize and carefully document results, as well as analyze and interpret results, and communicate findings through presentations. 

 

Reports to:       Principal Scientist of Cell Therapy Process Development

Location:          Thousand Oaks (NW Los Angeles area), CA

 

Primary Responsibilities

  • Designs and executes studies to improve product quality and process efficiencies, including process development studies to develop a thorough understanding of operating and performance parameters (design space).
  • Performs gap analysis, identify problems and deficiencies, as well as provide recommendations for studies and solutions to manufacturing processes.
  • Uses engineering approaches to optimize manufacturing process parameters.
  • Performs cell-based assays as well as flow cytometry for process assessment and product characterization.
  • Documents laboratory procedures and experiments with great attention to detail in laboratory notebooks.
  • Assists in the development of standard operating procedures, batch records, and analytical sampling plans.

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Qualifications

Education and Experience

  • PhD in a biological or engineering science with 2-5 years of industry related experience, Master’s Degree with 3-9+ years of related industry experience or Bachelor’s Degree with 5-12+ years of experience.
  • Knowledge and experience in mammalian cell culture / biotechnology related development (bioreactor operations, aseptic operations, cell biology, biochemistry).
  • Experience with scale-up process development and process characterization.
  • Basic analytical skills including the following techniques: multicolor flow cytometry, cell-based bioassays, ELISA, etc. are preferred but not required.
  • Ability to follow laboratory procedures with attention to detail, and successfully execute experiments at the bench.
  • Comfortable in a fast-paced small company environment and able to adjust workload based upon changing priorities.
  • Demonstrated ability to maintain lab execution records and perform data analysis.

 Preferred

  • Prior experience handling T-cell culture in cell biology space.
  • Familiarity with development and/or commercialization of cell-based therapeutics.
  • Basic understanding of cGMP requirements.
  • Experience using SAS JMP for Design of Experiment (DOE) and data analysis.

More about Atara Bio

We launched Atara Biotherapeutics in August 2012 to help patients with serious diseases and few therapeutic options. We’re named after Atara Ciechanover who suffered from cancer before passing away. We are considered a leading off-the-shelf T-cell immunotherapy company (Nasdaq ATRA) developing novel treatments for patients with cancer, autoimmune and viral diseases.

 

We’re proud of our team of 350+ Atarians co-located by design in South San Francisco (corporate headquarters) and Southern California (R&D and manufacturing headquarters in the northwest Los Angeles area) with a newly-established European headquarters in Zug, Switzerland. Atara also has a R&D site in the Denver, Colorado area and an office in New York City. Our Southern California hub is anchored by a new 90,000 sq. ft., state-of-the-art Atara T-Cell Operations and Manufacturing (ATOM) facility in Thousand Oaks, California.

Our mission – “Transform the lives of patients with serious medical conditions through pioneering science, teamwork, and a commitment to excellence.”

 

Our vision - “T-Cell Immunotherapy for every patient, any time.”

 

Visit www.atarabio.com to learn more.

Atara Bio is an equal opportunity employer and makes employment decisions on the basis of merit and other lawful factors. In accordance with applicable law, the Company prohibits discrimination based on race, color, religion, creed, sex, gender (including pregnancy, childbirth or medical condition related to pregnancy or childbirth), gender identity, expression or dysphoria, marital status, age, national origin or ancestry, physical or mental disability, medical condition, genetic information, veteran status, caregiver status, sexual orientation, transgender status or any other classification protected by federal, state or local laws or because of the individual’s association with a member of a protected group or connection to an organization or group related to a protected group.

We comply with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must have authorization to work for Atara Bio in the United States.
 
 

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